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Generated: July 22, 2019

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Patent: 9,051,561

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Summary for Patent: 9,051,561
Title:Asparaginase and treating diseases associated with asparagine dependence
Abstract: Disclosed herein are polypeptides which exhibit asparaginase activity and little to no glutaminase activity. The polypeptides have sequences which correspond to W. succinogenes asparaginase, but have an amino acid residue other than proline at amino acid position 121. The polypeptides exhibit higher kinetic rates of asparaginase activity to glutaminase activity as compared to W. succinogenes asparaginase and Elspar.RTM., an E. coli asparaginase.
Inventor(s): Durden; Donald (La Jolla, CA)
Assignee: Children\'s Hospital Los Angeles (Los Angeles, CA)
Application Number:14/348,637
Patent Claims:see list of patent claims

Details for Patent 9,051,561

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Patent Expiration Status Orphan Source
Merck ELSPAR asparaginase VIAL 101063 001 1978-01-10 ➤ Try a Free Trial Children\'s Hospital Los Angeles (Los Angeles, CA) ➤ Try a Free Trial RX search
Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Patent Expiration Status Orphan Source

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