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Last Updated: August 11, 2020

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Patent: 9,040,034

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Summary for Patent: 9,040,034
Title:Vitamin functionalized gel-forming block copolymers for biomedical applications
Abstract: Gel-forming block copolymers were prepared comprising i) a central hydrophilic block consisting essentially of a divalent poly(ethylene oxide) chain and ii) two peripheral monocarbonate or polycarbonate hydrophobic blocks. The hydrophobic blocks comprise one or more vitamin-bearing subunits. The vitamin-bearing subunits comprise a carbonate backbone portion and a side chain comprising a covalently bound form of a vitamin. The gel-forming block copolymers can be used to prepare various biodegradable and/or biocompatible hydrogel and organogel drug compositions, in particular antimicrobial and/or anti-tumor drug compositions. The hydrogel compositions can be suitable for depot injections. Synergistic enhancement of toxicity to microbes was observed with compositions comprising an antimicrobial cationic polymer and an antimicrobial compound.
Inventor(s): Hedrick; James L. (Pleasanton, CA), Lee; Ashlynn L. Z. (Singapore, SG), Ng; Victor W. L. (Singapore, SG), Yang; Yi Yan (Singapore, SG)
Assignee: International Business Machines Corporation (Armonk, NY) Agency for Science, Technology and Research (Singapore, SG)
Application Number:13/859,062
Patent Claims:see list of patent claims

Details for Patent 9,040,034

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Genentech HERCEPTIN trastuzumab VIAL; INTRAVENOUS 103792 001 1998-09-25   Start Trial International Business Machines Corporation (Armonk, NY) Agency for Science, Technology and Research (Singapore, SG) 2039-02-26 RX Orphan search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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