Make Better Decisions - Finding and Evaluating Generic and Branded Drug Market Entry Opportunities

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Finding and Evaluating Generic and Branded Drug Market Entry Opportunities

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Generated: July 17, 2019

DrugPatentWatch Database Preview

Patent: 9,028,800

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Summary for Patent: 9,028,800
Title:Methods and compositions for improved F-18 labeling of proteins, peptides and other molecules
Abstract: The present application discloses compositions and methods of synthesis and use of .sup.18F or .sup.19F-labeled molecules of use in PET, SPECT and/or MR imaging. Preferably, the .sup.18F or .sup.19F is conjugated to a targeting molecule by formation of a complex with a group IIIA metal and binding of the complex to a bifunctional chelating agent, which may be directly or indirectly attached to the targeting molecule. In other embodiments, the .sup.18F or .sup.19F labeled moiety may comprise a targetable construct used in combination with a bispecific antibody to target a disease-associated antigen. The disclosed methods and compositions allow the simple and reproducible labeling of molecules at very high efficiency and specific activity in 30 minutes or less. In preferred embodiments, the labeled molecule may be used for imaging in a subject without purification after labeling.
Inventor(s): D\'Souza; Christopher A. (Pomona, NY), McBride; William J. (Boonton, NJ), Goldenberg; David M. (Mendham, NJ)
Assignee: Immunomedics, Inc. (Morris Plains, NJ)
Application Number:14/273,163
Patent Claims:see list of patent claims

Details for Patent 9,028,800

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Patent Expiration Status Orphan Source
Biogen ZINBRYTA daclizumab INJECTABLE;INJECTION 761029 001 2016-05-27 ➤ Sign Up Immunomedics, Inc. (Morris Plains, NJ) ➤ Sign Up RX search
Genentech ACTEMRA tocilizumab INJECTABLE;INTRAVENOUS, SUBCUTANEOUS 125472 001 2013-10-21 ➤ Sign Up Immunomedics, Inc. (Morris Plains, NJ) ➤ Sign Up RX search
Human Genome Sciences Inc. BENLYSTA belimumab INJECTABLE; INJECTION 125370 002 2011-03-09 ➤ Sign Up Immunomedics, Inc. (Morris Plains, NJ) ➤ Sign Up RX search
Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Patent Expiration Status Orphan Source

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Serving hundreds of leading biopharmaceutical companies globally:

Argus Health
Chinese Patent Office
UBS
Mallinckrodt
Teva
Medtronic

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