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Generated: September 18, 2019

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Patent: 9,017,726

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Summary for Patent: 9,017,726
Title:Biodegradable and thermosensitive poly(organophosphazene)-superparamagnetic nanoparticle complex, preparation method and use thereof
Abstract: The present invention relates to a poly(organophosphazene)-superparamagnetic nanoparticle complex including a biodegradable and thermosensitive poly(organophosphazene) and a iron oxide (Fe.sub.3O.sub.4, Magnetite)-series ferrite superparamagnetic nanoparticle, a preparation method, and uses of carrying a physiologically-active material, a bio-material and a biomaterial for cancer hyperthermia. The iron oxide is used as a MRI contrast agent for T.sub.-2 and T.sub.2* weighted image, and the poly(organophosphazene) shows a sol-to-gel behavior depending upon the temperature change. The complex is a bound-type where the superparamagnetic ferrite nanoparticle is bonded to phosphazene-based polymer via hydrophobic binding, and a mixed-type where the superparamagnetic ferrite nanoparticle is physically mixed with the phosphazene-based polymer.
Inventor(s): Song; Soo-Chang (Seoul, KR), Kim; Jang Il (Seongnam-si, KR)
Assignee: Korea Institute of Science and Technology (Seoul, KR)
Application Number:13/173,756
Patent Claims:see list of patent claims

Details for Patent 9,017,726

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Merck ELSPAR asparaginase VIAL 101063 001 1978-01-10   Try a Free Trial Korea Institute of Science and Technology (Seoul, KR) 2030-06-30 RX search
Biovitrum Ab KINERET anakinra VIAL; SUBCUTANEOUS 103950 001 2001-11-14   Try a Free Trial Korea Institute of Science and Technology (Seoul, KR) 2030-06-30 RX search
Biovitrum Ab KINERET anakinra VIAL; SUBCUTANEOUS 103950 002 2001-11-14   Try a Free Trial Korea Institute of Science and Technology (Seoul, KR) 2030-06-30 RX search
Biovitrum Ab KINERET anakinra VIAL; SUBCUTANEOUS 103950 003 2001-11-14   Try a Free Trial Korea Institute of Science and Technology (Seoul, KR) 2030-06-30 RX search
Imclone ERBITUX cetuximab VIAL; INTRAVENOUS 125084 001 2004-06-18   Try a Free Trial Korea Institute of Science and Technology (Seoul, KR) 2030-06-30 RX Orphan search
Genentech AVASTIN bevacizumab VIAL; INTRAVENOUS 125085 001 2004-02-26   Try a Free Trial Korea Institute of Science and Technology (Seoul, KR) 2030-06-30 RX search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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Serving hundreds of leading biopharmaceutical companies globally:

Deloitte
US Department of Justice
Chinese Patent Office
McKinsey
Johnson and Johnson
Mallinckrodt

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