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Last Updated: September 19, 2020

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Patent: 8,999,326

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Summary for Patent: 8,999,326
Title:Oncotherapeutic application of inhibitors of high-affinity glucose transporters
Abstract: The subject invention concerns materials and methods for treating oncological disorders in a person or animal using any agent or compound that inhibits uptake of glucose into a cell. The subject invention also concerns methods for inducing apoptosis and inhibiting the proliferation or survival of a cell. In one embodiment, the methods comprise administering an effective amount of an agent or compound that inhibits the activity of one or more glucose transporter proteins, such as Glut-1. An antibody that binds to and inhibits a glucose transporter protein can be used in the present methods.
Inventor(s): Simon; George R. (Huntingdon Valley, PA)
Assignee: University of South Florida (Tampa, FL)
Application Number:12/673,677
Patent Claims:see list of patent claims

Details for Patent 8,999,326

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Merck ELSPAR asparaginase VIAL 101063 001 1978-01-10   Start Trial University of South Florida (Tampa, FL) 2027-08-17 RX search
Organon Usa Inc. TICE BCG bacillus calmette-guerin POWDER, FOR SUSPENSION 102821 1 1990-08-24   Start Trial University of South Florida (Tampa, FL) 2027-08-17 search
Schering INTRON A interferon alfa-2b VIAL 103132 001 1986-06-04   Start Trial University of South Florida (Tampa, FL) 2027-08-17 RX search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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