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Generated: September 22, 2019

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Patent: 8,992,908

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Summary for Patent: 8,992,908

Title:	Anti-IL-6 antibodies for the treatment of oral mucositis
Abstract:	The present invention is directed to therapeutic methods using IL-6 antagonists such as anti-IL-6 antibodies and fragments thereof having binding specificity for IL-6 to prevent or treat mucositis (e.g., oral mucositis) including persons on a treatment regimen with a drug or chemotherapy and/or radiation for cancer (e.g., head and neck cancer) that is associated with increased risk of mucositis, including oral mucositis.
Inventor(s):	Smith; Jeffrey T.L. (Bellevue, WA), Garcia-Martinez; Leon F. (Woodinville, WA), Feldhaus; Andrew L. (Lynnwood, WA)
Assignee:	Alderbio Holdings LLC (Las Vegas, NV)
Application Number:	13/304,173
Patent Claims:	see list of patent claims

Details for Patent 8,992,908

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Applicant	Tradename	Biologic Ingredient	Dosage Form	BLA	Number	Approval Date	Patent No.	Assignee	Estimated Patent Expiration	Status	Orphan	Source
Merck	ELSPAR	asparaginase	VIAL	101063	001	1978-01-10	Try a Free Trial	Alderbio Holdings LLC (Las Vegas, NV)	2036-04-30	RX		search
Genentech	HERCEPTIN	trastuzumab	VIAL; INTRAVENOUS	103792	001	1998-09-25	Try a Free Trial	Alderbio Holdings LLC (Las Vegas, NV)	2036-04-30	RX	Orphan	search
Genzyme	CAMPATH	alemtuzumab	VIAL; INTRAVENOUS	103948	001	2001-05-07	Try a Free Trial	Alderbio Holdings LLC (Las Vegas, NV)	2036-04-30	RX	Orphan	search
Genzyme	CAMPATH	alemtuzumab	VIAL; INTRAVENOUS	103948	002	2001-05-07	Try a Free Trial	Alderbio Holdings LLC (Las Vegas, NV)	2036-04-30	RX	Orphan	search
Genzyme	LEMTRADA	alemtuzumab	INJECTABLE;INJECTION	103948	003	2001-05-07	Try a Free Trial	Alderbio Holdings LLC (Las Vegas, NV)	2036-04-30	RX	Orphan	search
>Applicant	>Tradename	>Biologic Ingredient	>Dosage Form	>BLA	>Number	>Approval Date	>Patent No.	>Assignee	>Estimated Patent Expiration	>Status	>Orphan	>Source

International Patent Family for US Patent 8,992,908

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Country	Patent Number	Publication Date
Argentina	074227	Dec 29, 2010
Australia	2007307324	Apr 17, 2008
Australia	2007307324	Aug 15, 2013
Australia	2008254578	Jun 06, 2013
Australia	2008254578	Nov 27, 2008
Australia	2008254584	Nov 27, 2008
>Country	>Patent Number	>Publication Date

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