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Patent: 8,992,908
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Summary for Patent: 8,992,908
| Title: | Anti-IL-6 antibodies for the treatment of oral mucositis |
| Abstract: | The present invention is directed to therapeutic methods using IL-6 antagonists such as anti-IL-6 antibodies and fragments thereof having binding specificity for IL-6 to prevent or treat mucositis (e.g., oral mucositis) including persons on a treatment regimen with a drug or chemotherapy and/or radiation for cancer (e.g., head and neck cancer) that is associated with increased risk of mucositis, including oral mucositis. |
| Inventor(s): | Smith; Jeffrey T.L. (Bellevue, WA), Garcia-Martinez; Leon F. (Woodinville, WA), Feldhaus; Andrew L. (Lynnwood, WA) |
| Assignee: | Alderbio Holdings LLC (Las Vegas, NV) |
| Application Number: | 13/304,173 |
| Patent Claims: | see list of patent claims |
Details for Patent 8,992,908
| Applicant | Tradename | Biologic Ingredient | Dosage Form | BLA | Number | Approval Date | Patent No. | Assignee | Estimated Patent Expiration | Status | Orphan | Source |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Genentech Inc | HERCEPTIN HYLECTA | trastuzumab; hyaluronidase-oysk | INJECTABLE;SUBCUTANEOUS | 761106 | 001 | 2019-02-28 | Start Trial | Alderbio Holdings LLC (Las Vegas, NV) | 2039-02-26 | RX | search | |
| Wyeth Pharms Inc | MYLOTARG | gemtuzumab ozogamicin | VIAL;SINGLE-DOSE | 761060 | 001 | 2018-04-09 | Start Trial | Alderbio Holdings LLC (Las Vegas, NV) | 2039-02-26 | RX | Orphan | search |
| Genzyme | LEMTRADA | alemtuzumab | INJECTABLE;INJECTION | 103948 | 003 | 2001-05-07 | Start Trial | Alderbio Holdings LLC (Las Vegas, NV) | 2039-02-26 | RX | Orphan | search |
| Genzyme | CAMPATH | alemtuzumab | VIAL; INTRAVENOUS | 103948 | 002 | 2001-05-07 | Start Trial | Alderbio Holdings LLC (Las Vegas, NV) | 2039-02-26 | RX | Orphan | search |
| >Applicant | >Tradename | >Biologic Ingredient | >Dosage Form | >BLA | >Number | >Approval Date | >Patent No. | >Assignee | >Estimated Patent Expiration | >Status | >Orphan | >Source |
International Patent Family for US Patent 8,992,908
| Country | Patent Number | Estimated Expiration |
|---|---|---|
| South Africa | 200908770 | Start Trial |
| World Intellectual Property Organization (WIPO) | 2008045140 | Start Trial |
| World Intellectual Property Organization (WIPO) | 2008144753 | Start Trial |
| World Intellectual Property Organization (WIPO) | 2008144757 | Start Trial |
| >Country | >Patent Number | >Estimated Expiration |
