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Last Updated: November 29, 2021

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Patent: 8,980,248

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Summary for Patent: 8,980,248
Title:Injectable polymer composition for use as a cell delivery vehicle
Abstract: This invention provides a polymer composition comprising at least one thermal gelling polymer and at least one anionic polymer for cell delivery applications. These injectable polymer compositions are shear-thinning, thixotropic and resorbable. More specifically there is described a hyaluronan (HA) and methylcellulose (MC) based thermogelling cell delivery system (HAMC) that promotes cell survival both in vitro and in vivo. Importantly, HAMC (relative to media alone) enhances survival of transplanted stem/progenitor cells in the injured CNS. HAMC provides a minimally-invasive cell delivery strategy where the microenvironment can be further defined and the differentiation and regenerative capacity further explored. This hydrogel system has applications for minimally-invasive cell delivery to other tissues/organs in the body as well.
Inventor(s): Shoichet; Molly Sandra (Toronto, CA), Zahir; Tasneem (Mississauga, CA), Ballios; Brian (Mississauga, CA), Van der Kooy; Derek (Toronto, CA), Cooke; Michael (Toronto, CA)
Assignee: The Governing Council of the University of Toronto (Toronto, Ontario, CA)
Application Number:13/516,846
Patent Claims:see list of patent claims

Details for Patent 8,980,248

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Emd Serono, Inc. PERGONAL menotropins For Injection 017646 1975-08-22 ⤷  Try it Free 2029-12-18
Emd Serono, Inc. PERGONAL menotropins For Injection 017646 1985-05-20 ⤷  Try it Free 2029-12-18
Organon Usa Inc., A Subsidiary Of Merck & Co., Inc. HUMEGON menotropins For Injection 020328 1994-09-01 ⤷  Try it Free 2029-12-18
Ferring Pharmaceuticals Inc. REPRONEX menotropins For Injection 021047 1999-08-27 ⤷  Try it Free 2029-12-18
Ferring Pharmaceuticals Inc. BRAVELLE urofollitropin For Injection 021289 2002-05-06 ⤷  Try it Free 2029-12-18
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

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