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Last Updated: December 5, 2019

DrugPatentWatch Database Preview

Patent: 8,969,008

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Summary for Patent: 8,969,008
Title:Genotoxic testing
Abstract: The present invention relates to methods for detecting for the presence of an agent that putatively causes or potentiates DNA damage comprising subjecting a cell (containing a DNA sequence encoding a reporter protein operatively linked to a human GADD45.alpha. gene promoter and a human GADD45.alpha. gene regulatory element arranged to activate expression of the DNA sequence in response to DNA damage) to an agent; and monitoring the expression of the reporter protein from the cell. The invention also concerns expression cassettes, vectors and cells which may be used according to such a method and also modified media that may be employed in fluorescence assays and in preferred embodiments of the method of the invention.
Inventor(s): Hastwell; Paul (Bedfordshire, GB), Walmsley; Richard (Marple, GB)
Assignee: Gentronix Limited (GB)
Application Number:13/860,061
Patent Claims:see list of patent claims

Details for Patent 8,969,008

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Schering INTRON A interferon alfa-2b VIAL 103132 003 1986-06-04   Start Trial Gentronix Limited (GB) 2024-05-20 RX search
Schering INTRON A interferon alfa-2b VIAL 103132 002 1986-06-04   Start Trial Gentronix Limited (GB) 2024-05-20 RX search
Schering INTRON A interferon alfa-2b VIAL 103132 001 1986-06-04   Start Trial Gentronix Limited (GB) 2024-05-20 RX search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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