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Last Updated: March 29, 2024

Patent: 8,968,719


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Summary for Patent: 8,968,719
Title:Live, oral vaccine for protection against Shigella dysenteriae serotype 1
Abstract: The invention relates to Salmonella typhi Ty21a comprising core-linked Shigella dysenteriae serotype 1 O-specific polysaccharide (O-Ps) and DNA encoding O antigen biosynthesis, said DNA selected from the group consisting of: a) the DNA sequence set out in any one of SEQ ID NOs: 1 and 2 and species homologs thereof; b) DNA encoding Shigella dysenteriae serotype 1 polypeptides encoded by any one of SEQ ID NOs: 1 and 2, and species homologs thereof; and c) DNA encoding a O antigen biosynthesis gene product that hybridizes under moderately stringent conditions to the DNA of (a) or (b); and related sequences, compositions of matter, vaccines, methods of using, and methods of making.
Inventor(s): Kopecko; Dennis J. (Silver Spring, MD), Xu; De-Qi (Columbia, MD)
Assignee: The United States of America, as represented by the Secretary, Department of Health and Human Sevices (Rockville, MD)
Application Number:14/145,104
Patent Claims:see list of patent claims

Details for Patent 8,968,719

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Emergent Travel Health, Inc. VIVOTIF typhoid vaccine live oral ty21a Capsule 103123 12/15/1989 ⤷  Try a Trial 2024-05-24
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

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