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Last Updated: September 22, 2020

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Patent: 8,956,643

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Summary for Patent: 8,956,643
Title:Porous biodegradable polymer scaffolds for in situ tissue regeneration and method for the preparation thereof
Abstract: The present invention relates to an intelligent porous biodegradable polymer scaffold for in situ tissue regeneration in which two kinds of physiologically active substances having high differentiation potential and biocompatibility are introduced into the polymer scaffold and conjugated to the surface thereof, respectively, and a method for the preparation thereof. Since the intelligent porous biodegradable polymer scaffold exhibits improved biocompatibility and differentiation potential due to the introduction of physiologically active substances capable of efficiently inducing cell proliferation and differentiation into both the surface and the inside thereof, it can directly induce in situ tissue regeneration of the musculoskeletal system from stem cells in a living tissue after transplanting the polymer scaffold and stem cells into a human body without additional in vitro cultivation. Therefore, the intelligent porous biodegradable polymer scaffold according to the present invention can be effectively used in the regeneration of various kinds of tissues and organs including the musculoskeletal system.
Inventor(s): Han; Dong Keun (Seoul, KR), Park; Kwideok (Seoul, KR), Kim; Jae-Jin (Seoul, KR), Bae; Soon Eon (Seoul, KR)
Assignee: Korea Institute of Science and Technology (Seoul, KR)
Application Number:12/473,850
Patent Claims:see list of patent claims

Details for Patent 8,956,643

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Nps Pharms Inc NATPARA parathyroid hormone INJECTABLE;INJECTION 125511 001 2015-01-23   Start Trial Korea Institute of Science and Technology (Seoul, KR) 2028-11-26 RX Orphan search
Nps Pharms Inc NATPARA parathyroid hormone INJECTABLE;INJECTION 125511 002 2015-01-23   Start Trial Korea Institute of Science and Technology (Seoul, KR) 2028-11-26 RX Orphan search
Nps Pharms Inc NATPARA parathyroid hormone INJECTABLE;INJECTION 125511 003 2015-01-23   Start Trial Korea Institute of Science and Technology (Seoul, KR) 2028-11-26 RX Orphan search
Nps Pharms Inc NATPARA parathyroid hormone INJECTABLE;INJECTION 125511 004 2015-01-23   Start Trial Korea Institute of Science and Technology (Seoul, KR) 2028-11-26 RX Orphan search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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