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Last Updated: September 22, 2020

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Patent: 8,951,790

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Summary for Patent: 8,951,790
Title:Mammalian expression vector pUHAB
Abstract: The present invention relates to the construction and utilization of a new mammalian expression vector that contains a unique multiple cloning site (MCS), designated pUHAB. The pUHAB vector comprises a high copy replication origin (ColE1), a drug resistance gene (TK-Hygromycin), and a human cytomegalovirus promoter operably associated with a unique intron (hCMV/intron). Further, pUHAB comprises a selectable marker conferring resistance to kanamycin in bacterial cells, and a phage f1(+) region. pUHAB can be used to transiently or stably express cloned genes when transfected into mammalian cells. The invention also encompasses kits and host cells and cell lines comprising pUHAB, and methods of producing a recombinant protein using pUHAB.
Inventor(s): Saha; Deba P. (Nutley, NJ)
Assignee: Merck Sharp & Dohme Corp. (Rahway, NJ)
Application Number:13/344,905
Patent Claims:see list of patent claims

Details for Patent 8,951,790

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Schering INTRON A interferon alfa-2b VIAL 103132 001 1986-06-04   Start Trial Merck Sharp & Dohme Corp. (Rahway, NJ) 2028-11-12 RX search
Schering INTRON A interferon alfa-2b VIAL 103132 002 1986-06-04   Start Trial Merck Sharp & Dohme Corp. (Rahway, NJ) 2028-11-12 RX search
Schering INTRON A interferon alfa-2b VIAL 103132 003 1986-06-04   Start Trial Merck Sharp & Dohme Corp. (Rahway, NJ) 2028-11-12 RX search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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