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Last Updated: October 18, 2021

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Patent: 8,944,072

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Summary for Patent: 8,944,072
Title:Thermal treatment process for tobacco materials
Abstract: A method of preparing a tobacco material for use in a smoking article is provided, including (i) mixing a tobacco material, water, and an additive selected from the group consisting of lysine, glycine, histidine, alanine, methionine, glutamic acid, aspartic acid, proline, phenylalanine, valine, arginine, di- and trivalent cations, asparaginase, saccharides, phenolic compounds, reducing agents, compounds having a free thiol group, oxidizing agents, oxidation catalysts, plant extracts, and combinations thereof; (ii) heating the mixture; and (iii) incorporating the heat-treated mixture into a smoking article as a smokable material. A smoking article in the form of a cigarette is also provided that includes a tobacco material pre-treated to inhibit reaction of asparagine to form acrylamide in mainstream smoke. Upon smoking, the smoking article is characterized by an acrylamide content of mainstream smoke that is reduced relative to an untreated control smoking article.
Inventor(s): Chen; Gong (Winston-Salem, NC), Gerardi; Anthony Richard (Winston-Salem, NC), Mua; John-Paul (Advance, NC), Holton, Jr.; Darrell Eugene (Clemmons, NC), Cantrell; Daniel Verdin (Lewisville, NC), St. Charles; Frank Kelley (Bowling Green, KY), Moldoveanu; Serban C. (Winston-Salem, NC), Brinkley; Paul Andrew (Winston-Salem, NC)
Assignee: R.J. Reynolds Tobacco Company (Winston-Salem, NC)
Application Number:12/855,343
Patent Claims:see list of patent claims

Details for Patent 8,944,072

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Merck ELSPAR asparaginase VIAL 101063 1978-01-10 ⤷  Free Forever Trial R.J. Reynolds Tobacco Company (Winston-Salem, NC) 2029-06-02 RX search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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