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Patent: 8,933,205
Summary for Patent: 8,933,205
Title: | Process for preparing purified drug conjugates |
Abstract: | The invention provides a process for preparing a cell-binding agent chemically coupled to a drug. The process comprises covalently attaching a linker to a cell-binding agent, a purification step, conjugating a drug to the cell-binding agent and a subsequent purification step. |
Inventor(s): | Dai; Yong (Newton, MA), Wang; Yong (North Attleboro, MA), Jin; Shengjin (Acton, MA), Meshulam; Deborah H. (Brookline, MA), Amphlett; Godfrey W. (Cambridge, MA) |
Assignee: | ImmunoGen, Inc. (Waltham, MA) |
Application Number: | 13/776,097 |
Patent Claims: | see list of patent claims |
Details for Patent 8,933,205
Applicant | Tradename | Biologic Ingredient | Dosage Form | BLA | Number | Approval Date | Patent No. | Assignee | Estimated Patent Expiration | Status | Orphan | Source |
---|---|---|---|---|---|---|---|---|---|---|---|---|
Genentech Inc | HERCEPTIN HYLECTA | trastuzumab; hyaluronidase-oysk | INJECTABLE;SUBCUTANEOUS | 761106 | 001 | 2019-02-28 | Start Trial | ImmunoGen, Inc. (Waltham, MA) | 2025-08-24 | RX | search | |
Genentech Inc | RITUXAN HYCELA | rituximab; hyaluronidase (human recombinant) | SOLUTION;SUBCUTANEOUS | 761064 | 002 | 2017-06-22 | Start Trial | ImmunoGen, Inc. (Waltham, MA) | 2025-08-24 | RX | Orphan | search |
Genentech Inc | RITUXAN HYCELA | rituximab; hyaluronidase (human recombinant) | SOLUTION;SUBCUTANEOUS | 761064 | 001 | 2017-06-22 | Start Trial | ImmunoGen, Inc. (Waltham, MA) | 2025-08-24 | RX | Orphan | search |
Genentech | HERCEPTIN | trastuzumab | VIAL; INTRAVENOUS | 103792 | 001 | 1998-09-25 | Start Trial | ImmunoGen, Inc. (Waltham, MA) | 2025-08-24 | RX | Orphan | search |
Genentech | RITUXAN | rituximab | VIAL | 103705 | 001 | 1997-11-26 | Start Trial | ImmunoGen, Inc. (Waltham, MA) | 2025-08-24 | RX | search | |
>Applicant | >Tradename | >Biologic Ingredient | >Dosage Form | >BLA | >Number | >Approval Date | >Patent No. | >Assignee | >Estimated Patent Expiration | >Status | >Orphan | >Source |
International Patent Family for US Patent 8,933,205
Country | Patent Number | Publication Date |
---|---|---|
South Africa | 200801564 | Jul 25, 2012 |
World Intellectual Property Organization (WIPO) | 2006086733 | Aug 17, 2006 |
World Intellectual Property Organization (WIPO) | 2006086733 | Jun 07, 2007 |
World Intellectual Property Organization (WIPO) | 2007024536 | Jul 05, 2007 |
World Intellectual Property Organization (WIPO) | 2007024536 | Mar 01, 2007 |
United States of America | 2006182750 | Aug 17, 2006 |
>Country | >Patent Number | >Publication Date |