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Generated: September 15, 2019

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Patent: 8,916,159

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Summary for Patent: 8,916,159
Title:Selenocysteine mediated hybrid antibody molecules
Abstract: The invention provides methods and compositions employing hybrid molecules of a synthetic molecule and antibody or antibody fragment comprising a selenocysteine residue, wherein the synthetic molecule is covalently linked to the antibody or antibody fragment at the selenocysteine residue. The invention also provides a composition comprising a hybrid molecule as described above and a pharmaceutically acceptable carrier. The invention further provides for methods of making the hybrid molecules, and methods of using the hybrid molecule described above to inhibit cell surface receptor binding.
Inventor(s): Rader; Christoph (Olney, MD), Hofer; Thomas (Zurich, CH), Burke, Jr.; Terrence (Bethesda, MD), Thomas; Joshua (Frederick, MD)
Assignee: The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, DC)
Application Number:12/570,796
Patent Claims:see list of patent claims

Details for Patent 8,916,159

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Genentech RITUXAN rituximab VIAL 103705 001 1997-11-26 ➤ Sign Up The United States of America, as represented by the Secretary, Department of Health and Human Services (Washington, DC) 2027-04-02 RX search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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