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Generated: September 23, 2019

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Patent: 8,895,281

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Summary for Patent: 8,895,281
Title:Method for preparing a site-specific physiologically active polypeptide conjugate
Abstract: The present invention provides a method for preparing a site-specific physiologically active polypeptide conjugate in a high yield by treating a physiologically active polypeptide with a non-peptidyl polymer in the presence of an alcohol at a specific pH, which can be desirably employed in the development of long acting formulations of various peptide drugs having high in-vivo activity and markedly prolonged in-blood half-life.
Inventor(s): Song; Dae Hae (Hwaseong-si, KR), Shin; Jae Hee (Suwon-si, KR), Lee; Jae Min (Seoul, KR), Park; Young Kyung (Suwon-si, KR), Kwon; Se Chang (Seoul, KR), Lee; Gwan Sun (Seoul, KR)
Assignee: Hanmi Science Co., Ltd (Hwaseong-si, KR)
Application Number:13/255,199
Patent Claims:see list of patent claims

Details for Patent 8,895,281

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Advance Biofactures SANTYL collagenase VIAL 101995 001 1965-06-04 ➤ Sign Up Hanmi Science Co., Ltd (Hwaseong-si, KR) 2029-03-20 RX search
Nps Pharms Inc NATPARA parathyroid hormone INJECTABLE;INJECTION 125511 001 2015-01-23 ➤ Sign Up Hanmi Science Co., Ltd (Hwaseong-si, KR) 2029-03-20 RX Orphan search
Nps Pharms Inc NATPARA parathyroid hormone INJECTABLE;INJECTION 125511 002 2015-01-23 ➤ Sign Up Hanmi Science Co., Ltd (Hwaseong-si, KR) 2029-03-20 RX Orphan search
Nps Pharms Inc NATPARA parathyroid hormone INJECTABLE;INJECTION 125511 003 2015-01-23 ➤ Sign Up Hanmi Science Co., Ltd (Hwaseong-si, KR) 2029-03-20 RX Orphan search
Nps Pharms Inc NATPARA parathyroid hormone INJECTABLE;INJECTION 125511 004 2015-01-23 ➤ Sign Up Hanmi Science Co., Ltd (Hwaseong-si, KR) 2029-03-20 RX Orphan search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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