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Generated: July 23, 2019

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Patent: 8,895,001

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Summary for Patent: 8,895,001
Title:Use of ErbB3 inhibitors in the treatment of triple negative and basal-like breast cancers
Abstract: Provided are methods of suppressing growth of triple negative breast tumors and basal-like breast tumors by contacting tumor cells with an ErbB3 inhibitor, e.g., an anti-ErbB3 antibody. Also provided are methods for treating triple negative breast cancer or basal-like breast cancer in a patient by administering to the patient an ErbB3 inhibitor, e.g., an anti-ErbB3 antibody. The treatment methods can further comprise selecting a patient having a triple negative breast cancer or basal-like breast cancer and then administering an ErbB3 inhibitor to the patient. The treatment methods also can further comprise administering at least one additional anti-cancer agent to the patient in combination with the ErbB3 inhibitor.
Inventor(s): Moyo; Victor (Concord, MA), Garcia; Gabriela (Roslindale, MA)
Assignee: Merrimack Pharmaceuticals, Inc. (Cambridge, MA)
Application Number:13/583,949
Patent Claims:see list of patent claims

Details for Patent 8,895,001

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Patent Expiration Status Orphan Source
Amgen VECTIBIX panitumumab INJECTABLE; IV (INFUSION) 125147 003 2006-09-27 ➤ Sign Up Merrimack Pharmaceuticals, Inc. (Cambridge, MA) ➤ Sign Up RX search
Amgen VECTIBIX panitumumab INJECTABLE; IV (INFUSION) 125147 002 2006-09-27 ➤ Sign Up Merrimack Pharmaceuticals, Inc. (Cambridge, MA) ➤ Sign Up RX search
Amgen VECTIBIX panitumumab INJECTABLE; IV (INFUSION) 125147 001 2006-09-27 ➤ Sign Up Merrimack Pharmaceuticals, Inc. (Cambridge, MA) ➤ Sign Up RX search
Genentech AVASTIN bevacizumab VIAL; INTRAVENOUS 125085 002 2004-02-26 ➤ Sign Up Merrimack Pharmaceuticals, Inc. (Cambridge, MA) ➤ Sign Up RX search
Genentech AVASTIN bevacizumab VIAL; INTRAVENOUS 125085 001 2004-02-26 ➤ Sign Up Merrimack Pharmaceuticals, Inc. (Cambridge, MA) ➤ Sign Up RX search
Imclone ERBITUX cetuximab VIAL; INTRAVENOUS 125084 001 2004-06-18 ➤ Sign Up Merrimack Pharmaceuticals, Inc. (Cambridge, MA) ➤ Sign Up RX Orphan search
Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Patent Expiration Status Orphan Source

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International Patent Family for US Patent 8,895,001

Country Patent Number Publication Date
South Africa 201206425 Aug 26, 2015
World Intellectual Property Organization (WIPO) 2011112953 Dec 01, 2011
World Intellectual Property Organization (WIPO) 2011112953 Sep 15, 2011
United States of America 2013034548 Feb 07, 2013
United States of America 2015132292 May 14, 2015
United States of America 2017291957 Oct 12, 2017
Country Patent Number Publication Date

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