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Last Updated: September 28, 2020

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Patent: 8,883,760

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Summary for Patent: 8,883,760
Title:Cancer therapy using beta glucan and antibodies
Abstract: The present invention relates to methods of using neutral soluble glucan and monoclonal antibodies for antitumor therapy. Neutral soluble Beta (1,3; 1,6) glucan (NSG) enhances the tumoricidal activity of the innate immune system by binding to the C3 complement protein receptor CR3. The glucan does not stimulate the induction of inflammatory cytokines. Also described are methods of using whole glucan particles (WGP) as an immunomodulator by inducing a shift from a Th2 response to the Th1 response, leading to an enhanced antitumor cytotoxic T-cell response.
Inventor(s): Ross; Gordon D. (Prospect, KY)
Assignee: University of Louisville Research Foundation, Inc. (Louisville, KY)
Application Number:10/526,185
Patent Claims:see list of patent claims

Details for Patent 8,883,760

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Genentech HERCEPTIN trastuzumab VIAL; INTRAVENOUS 103792 001 1998-09-25   Start Trial University of Louisville Research Foundation, Inc. (Louisville, KY) 2022-09-04 RX Orphan search
Genentech Inc HERCEPTIN HYLECTA trastuzumab; hyaluronidase-oysk INJECTABLE;SUBCUTANEOUS 761106 001 2019-02-28   Start Trial University of Louisville Research Foundation, Inc. (Louisville, KY) 2022-09-04 RX search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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