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Last Updated: September 29, 2020

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Patent: 8,852,877

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Summary for Patent: 8,852,877
Title:Apparatus and method for identifying a hook effect and expanding the dynamic range in point of care immunoassays
Abstract: The present invention relates to systems and methods for the rapid in situ determination of the existence of a hook effect and expansion of the dynamic range of a point of care immunoassay. For example, a system for identifying a hook effect and expanding the dynamic range of an immunoassay is provided that may include a primary sensor having first immobilized antibodies that may be configured to generate a first signal based on a presence or absence of a target analyte in a sample. The system may further include an attenuated sensor having second immobilized antibodies at a reduced concentration relative to a concentration of the first immobilized antibodies on the primary sensor and that may be configured to generate a second signal based on the presence or absence of the target analyte in the sample. The system may further include a processor configured to determine a presence of a hook effect in the immunoassay based on relative values of the first and second signals and optionally determine the target analyte concentration of the sample.
Inventor(s): Campbell; John (Woodlawn, CA), Nguyen; Linda (Gloucester, CA), Smith; James (North Gower, CA), Weiss; Wenda (Munster, CA)
Assignee: Abbott Point of Care Inc. (Princeton, NJ)
Application Number:14/141,837
Patent Claims:see list of patent claims

Details for Patent 8,852,877

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Ferring CHORIONIC GONADOTROPIN gonadotropin, chorionic INJECTABLE;INJECTION 017016 004 1975-06-26   Start Trial Abbott Point of Care Inc. (Princeton, NJ) 2032-12-28 RX search
Ferring CHORIONIC GONADOTROPIN gonadotropin, chorionic INJECTABLE;INJECTION 017016 006 1975-06-26   Start Trial Abbott Point of Care Inc. (Princeton, NJ) 2032-12-28 RX search
Ferring CHORIONIC GONADOTROPIN gonadotropin, chorionic INJECTABLE;INJECTION 017016 007 1975-06-26   Start Trial Abbott Point of Care Inc. (Princeton, NJ) 2032-12-28 RX search
Ferring CHORIONIC GONADOTROPIN gonadotropin, chorionic INJECTABLE;INJECTION 017016 009 1975-06-26   Start Trial Abbott Point of Care Inc. (Princeton, NJ) 2032-12-28 RX search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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