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Last Updated: September 20, 2020

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Patent: 8,852,240

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Summary for Patent: 8,852,240
Title:Methods and compositions for fostering and preserving bone growth
Abstract: A method for augmenting bone in a subject in need thereof including installing within an interior portion of a bone located in the subject a sufficient amount of a biocompatible material to form a scaffold within the bone interior, wherein the scaffold serves as a support for the formation of new bone within the bone interior portion, and administering to the subject a sufficient amount of at least one bone augmentation agent to elevate blood concentration of at least one anabolic agent in the subject. The method may further include administering at least one anti-resorptive agent to the subject in an amount sufficient to substantially prevent resorption of new bone growth. In another embodiment, the method may further include a step of mechanically inducing an increase in osteoblast activity in the subject, wherein the elevation in blood concentration of the anabolic agent and the increase in osteoblast activity at least partially overlap in time.
Inventor(s): Vignery; Agnes (Branford, CT), Mehta; Nozer M. (Randolph, NJ), Gilligan; James P. (Union, NJ), Murphy; Kieran P. (Baltimore, MD)
Assignee: Kieran Murphy, LLC (Towson, MD) Yale University (New Haven, CT)
Application Number:11/796,439
Patent Claims:see list of patent claims

Details for Patent 8,852,240

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Nps Pharms Inc NATPARA parathyroid hormone INJECTABLE;INJECTION 125511 001 2015-01-23   Start Trial Kieran Murphy, LLC (Towson, MD) Yale University (New Haven, CT) 2024-10-25 RX Orphan search
Nps Pharms Inc NATPARA parathyroid hormone INJECTABLE;INJECTION 125511 002 2015-01-23   Start Trial Kieran Murphy, LLC (Towson, MD) Yale University (New Haven, CT) 2024-10-25 RX Orphan search
Nps Pharms Inc NATPARA parathyroid hormone INJECTABLE;INJECTION 125511 003 2015-01-23   Start Trial Kieran Murphy, LLC (Towson, MD) Yale University (New Haven, CT) 2024-10-25 RX Orphan search
Nps Pharms Inc NATPARA parathyroid hormone INJECTABLE;INJECTION 125511 004 2015-01-23   Start Trial Kieran Murphy, LLC (Towson, MD) Yale University (New Haven, CT) 2024-10-25 RX Orphan search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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