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Generated: September 22, 2019

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Patent: 8,828,668

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Summary for Patent: 8,828,668
Title:Markers for determination of patient responsiveness
Abstract: Compositions and methods are provided for prognostic classification of inflammatory diseases, e.g. inflammatory demyelinating disease, patients into subtypes, which subtypes are informative of the patient\'s need for therapy and responsiveness to a therapy of interest. The patterns of cytokines provides for a signature pattern that can identify patients likely to benefit from therapeutic intervention as well as discriminate patients that have a high probability of responsiveness to a therapy from those that have a low probability of responsiveness. Assessment of this signature pattern thus allows improved methods of care. In one embodiment of the invention, the autoimmune disease is multiple sclerosis or neuromyelitis optica.
Inventor(s): Axtell; Robert C. (Menlo Park, CA), Steinman; Lawrence (Stanford, CA), Han; May H. (Menlo Park, CA), de Jong; Brigit A. (Nijmegen, NL), Raman; Chander (Birmingham, AL), Walker; Michael (Carlsbad, CA), Shi; Jing (Carlsbad, CA)
Assignee: The Board of Trustees of the Leland Stanford Junior University (Palo Alto, CA)
Application Number:13/026,173
Patent Claims:see list of patent claims

Details for Patent 8,828,668

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Bayer Healthcare Pharms BETASERON interferon beta-1b VIAL; SUBCUTANEOUS 103471 001 1993-07-23   Try a Free Trial The Board of Trustees of the Leland Stanford Junior University (Palo Alto, CA) 2036-04-30 RX Orphan search
Serono Inc REBIF interferon beta-1a SYRINGE 103780 001 2002-03-07   Try a Free Trial The Board of Trustees of the Leland Stanford Junior University (Palo Alto, CA) 2036-04-30 RX search
Serono Inc REBIF interferon beta-1a SYRINGE 103780 002 2002-03-07   Try a Free Trial The Board of Trustees of the Leland Stanford Junior University (Palo Alto, CA) 2036-04-30 RX search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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