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Generated: July 23, 2019

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Patent: 8,815,879

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Summary for Patent: 8,815,879
Title:Substituted 4-(selenophen-2(or-3)-ylamino)pyrimidine compounds and methods of use thereof
Abstract: Selenophene compounds of formula (I) are described herein. In the compounds of Formula (I), ring A is a 6-membered aromatic fused ring, optionally containing one, two or three nitrogen atoms; a 5-membered heteroaromatic fused ring; or a mono- or bicyclic saturated heterocyclic fused ring having at least one ring member selected from the group consisting of N, O, S, SO and SO.sub.2; Y in ring B is nitrogen or substituted carbon; X is NR.sup.6, O, S, S(O), or S(O).sub.2. R.sup.1, R.sup.2, R.sup.3, R.sup.4, and R.sup.6 are defined in the specification. Selenophene compounds of formula (I) may be used in methods of treating cell proliferative disorders, particularly cancer. Pharmaceutical compositions containing selenophene compounds of formula (I) may be used for treatment, inhibition, or control of cancer. ##STR00001##
Inventor(s): Kasina; Sudhakar (Mercer Island, WA), Gokaraju; Ganga Raju (Vijayawada, IN), Somepalli; Venkateswarlu (Vijayawada, IN), Gokaraju; Rama Raju (Vijayawada, IN), Gokaraju; Venkata Kanaka Ranga Raju (Vijayawada, IN), Bhupathiraju; Kiran (Vijayawada, IN), Golakoti; Trimurtulu (Vijayawada, IN), Sengupta; Krishanu (Vijayawada, IN), Alluri; Venkata Krishna Raju (Vijayawada, IN)
Assignee: Kasina Laila Innova Pharmaceuticals Private Limited (Vijayawada, IN)
Application Number:13/896,538
Patent Claims:see list of patent claims

Details for Patent 8,815,879

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Patent Expiration Status Orphan Source
Genentech PERJETA pertuzumab VIAL; SINGLE-USE 125409 001 2012-06-08 ➤ Sign Up Kasina Laila Innova Pharmaceuticals Private Limited (Vijayawada, IN) ➤ Sign Up RX search
Regeneron Pharmaceuticals EYLEA aflibercept INJECTABLE; INJECTION 125387 001 2011-11-18 ➤ Sign Up Kasina Laila Innova Pharmaceuticals Private Limited (Vijayawada, IN) ➤ Sign Up RX search
Bristol Myers Squibb YERVOY ipilimumab INJECTABLE; INJECTION 125377 001 2011-03-25 ➤ Sign Up Kasina Laila Innova Pharmaceuticals Private Limited (Vijayawada, IN) ➤ Sign Up RX search
Genentech LUCENTIS ranibizumab INJECTABLE; INJECTION 125156 001 2006-06-30 ➤ Sign Up Kasina Laila Innova Pharmaceuticals Private Limited (Vijayawada, IN) ➤ Sign Up RX search
Amgen VECTIBIX panitumumab INJECTABLE; IV (INFUSION) 125147 003 2006-09-27 ➤ Sign Up Kasina Laila Innova Pharmaceuticals Private Limited (Vijayawada, IN) ➤ Sign Up RX search
Amgen VECTIBIX panitumumab INJECTABLE; IV (INFUSION) 125147 002 2006-09-27 ➤ Sign Up Kasina Laila Innova Pharmaceuticals Private Limited (Vijayawada, IN) ➤ Sign Up RX search
Amgen VECTIBIX panitumumab INJECTABLE; IV (INFUSION) 125147 001 2006-09-27 ➤ Sign Up Kasina Laila Innova Pharmaceuticals Private Limited (Vijayawada, IN) ➤ Sign Up RX search
Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Patent Expiration Status Orphan Source

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Mallinckrodt
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AstraZeneca
QuintilesIMS
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