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Generated: July 21, 2019

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Patent: 8,815,508

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Summary for Patent: 8,815,508
Title:Method of identifying disease risk factors
Abstract: Provided herein is a method for identifying a genetic variant that is associated with development of a condition of interest (e.g., Alzheimer\'s disease), and genetic variants so identified. Methods of treatment with an active agent (e.g., with a particular active agent and/or at an earlier age) is also provided, upon detecting a genetic variant described herein. In some embodiments, the genetic variant is a deletion/insertion polymorphism (DIP) of the TOMM40 gene. Kits for determining if a subject is at increased risk of developing late onset Alzheimer\'s disease is also provided. Kits for determining if a subject is responsive to treatment for a condition of interest with an active agent are further provided.
Inventor(s): Roses; Allen D. (Chapel Hill, NC)
Assignee: Zinfandel Pharmaceuticals, Inc. (Durham, NC)
Application Number:13/058,724
Patent Claims:see list of patent claims

Details for Patent 8,815,508

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Patent Expiration Status Orphan Source
Schering INTRON A interferon alfa-2b VIAL 103132 003 1986-06-04 ➤ Sign Up Zinfandel Pharmaceuticals, Inc. (Durham, NC) ➤ Sign Up RX search
Schering INTRON A interferon alfa-2b VIAL 103132 002 1986-06-04 ➤ Sign Up Zinfandel Pharmaceuticals, Inc. (Durham, NC) ➤ Sign Up RX search
Schering INTRON A interferon alfa-2b VIAL 103132 001 1986-06-04 ➤ Sign Up Zinfandel Pharmaceuticals, Inc. (Durham, NC) ➤ Sign Up RX search
Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Patent Expiration Status Orphan Source

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International Patent Family for US Patent 8,815,508

Country Patent Number Publication Date
South Africa 201101095 Jul 25, 2012
World Intellectual Property Organization (WIPO) 2010019550 Apr 22, 2010
World Intellectual Property Organization (WIPO) 2010019550 Feb 18, 2010
World Intellectual Property Organization (WIPO) 2010019550 Jan 13, 2011
World Intellectual Property Organization (WIPO) 2012096680 Jul 19, 2012
United States of America 2011166185 Jul 07, 2011
United States of America 2011189165 Aug 04, 2011
Country Patent Number Publication Date

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