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Last Updated: September 18, 2020

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Patent: 8,790,896

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Summary for Patent: 8,790,896
Title:Method for increasing protein expression in cells
Abstract: The present invention relates to a method for increasing the expression of a protein in cells, preferably in eukaryotic cells, by reducing the number of RNase L cleavage sites in the coding and/or non-coding region of the nucleic acid sequence of said protein. Furthermore, it relates to nucleic acid sequences exhibiting a reduced number of RNase L cleavage sites as well as to the proteins translated from such sequences.
Inventor(s): Khabar; Khalid S. (Riyadh, SA)
Assignee: King Faisal Specialist Hospital & Research Centre (Riyadh, SA) Terramark Markencreation GmbH (Bremen, DE)
Application Number:13/144,621
Patent Claims:see list of patent claims

Details for Patent 8,790,896

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Schering INTRON A interferon alfa-2b VIAL 103132 001 1986-06-04   Start Trial King Faisal Specialist Hospital & Research Centre (Riyadh, SA) Terramark Markencreation GmbH (Bremen, DE) 2029-01-19 RX search
Schering INTRON A interferon alfa-2b VIAL 103132 002 1986-06-04   Start Trial King Faisal Specialist Hospital & Research Centre (Riyadh, SA) Terramark Markencreation GmbH (Bremen, DE) 2029-01-19 RX search
Schering INTRON A interferon alfa-2b VIAL 103132 003 1986-06-04   Start Trial King Faisal Specialist Hospital & Research Centre (Riyadh, SA) Terramark Markencreation GmbH (Bremen, DE) 2029-01-19 RX search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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