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Last Updated: November 27, 2021

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Patent: 8,784,862

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Summary for Patent: 8,784,862
Title:Compounds and method for coating surfaces in a hemocompatible manner
Abstract: The invention concerns oligosaccharides and polysaccharides as well as the use of these oligosaccharides and/or polysaccharides, which contain the sugar unit N-acylglucosamine or N-acylgalactosamine for the production of hemocompatible surfaces as well as methods for the hemocompatible coating of surfaces with said oligosaccharides and/or polysaccharides, which imitate the common biosynthetic precursor substance of heparin, heparan sulphates and chitosan. The invention further describes methods for producing said oligosaccharides and/or polysaccharides and discloses various possibilities of using hemocompatibly coated surfaces. The invention relates particularly to the use of said oligosaccharides and/or polysaccharides on stents with at least one according to invention deposited hemocompatible coating, which contains an antiproliferative, antiinflammatory and/or antithrombotic active agent, methods for the preparation of said stents as well as the use of said stents for the prevention of restenosis.
Inventor(s): Horres; Roland (Stolberg, DE), Linssen; Marita Katharina (G ttingen, DE), Hoffmann; Michael (Eschweiler, DE), Hoffmann; Erika (Eschweiler, DE), DiBiase; Donate (Aachen, DE), Faust; Volker (Aachen, DE)
Assignee: Hemoteq AG (Wurselen, DE)
Application Number:12/827,710
Patent Claims:see list of patent claims

Details for Patent 8,784,862

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Microbix Biosystems Inc. KINLYTIC urokinase For Injection 021846 1978-01-16 ⤷  Try it Free 2022-05-10
Recordati Rare Diseases, Inc. ELSPAR asparaginase For Injection 101063 1978-01-10 ⤷  Try it Free 2022-05-10
Clinigen, Inc. PROLEUKIN aldesleukin For Injection 103293 1992-05-05 ⤷  Try it Free 2022-05-10
Amgen, Inc. NEUPOGEN filgrastim Injection 103353 1991-02-20 ⤷  Try it Free 2022-05-10
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

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