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Last Updated: December 8, 2021

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Patent: 8,778,620

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Summary for Patent: 8,778,620
Title:Methods for diagnosis, prognosis and methods of treatment
Abstract: The present invention provides an approach for the determination of the activation states of a plurality of proteins in single cells. This approach permits the rapid detection of heterogeneity in a complex cell population based on activation states, expression markers and other criteria, and the identification of cellular subsets that exhibit correlated changes in activation within the cell population. Moreover, this approach allows the correlation of cellular activities or properties. In addition, the use of modulators of cellular activation allows for characterization of pathways and cell populations. Several exemplary diseases that can be analyzed using the invention include AML, MDS, and MPN.
Inventor(s): Fantl; Wendy J. (San Francisco, CA), Rosen; David B. (San Francisco, CA), Cesano; Alessandra (Redwood City, CA), Putta; Santosh K. (Foster City, CA), Nolan; Garry (San Francisco, CA), Cohen; Aileen (Palo Alto, CA), Evensen; Erik (Foster City, CA)
Assignee: Nodality, Inc. (South San Francisco, CA)
Application Number:13/473,829
Patent Claims:see list of patent claims

Details for Patent 8,778,620

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Genentech, Inc. AVASTIN bevacizumab Injection 125085 2004-02-26 ⤷  Free Forever Trial 2028-07-10
Wyeth Pharmaceuticals Inc. MYLOTARG gemtuzumab ozogamicin For Injection 761060 2017-09-01 ⤷  Free Forever Trial 2028-07-10
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

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