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Last Updated: August 4, 2020

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Patent: 8,765,471

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Summary for Patent: 8,765,471
Title:Neutral protease (NP) and product by using neutral protease for tissue dissociation as well as method for the production thereof
Abstract: The use of a neutral protease (NP) together with a collagenase consists in that a neutral protease which is not contained in a collagenase enzyme preparation and which is not produced by a recombinant production is mixed before the beginning of a tissue dissociation with a collagenase or a collagenase enzyme preparation with an individual dosage of the quantitative proportions of neutral protease and collagenase for improving the isolation results with respect to yield, viability and integrity of the cells.
Inventor(s): Kurfuerst; Manfred (Moorrege, DE), Raemsch; Christian (Uetersen, DE), Raemsch-Guenther; Nicole (Uetersen, DE), Friedrich; Olaf (Tornesch, DE), Huettler; Silke (Uetersen, DE), Brandhorst; Daniel (Linden, DE), Berney; Thierry (Arenthon, FR), Bucher; Pascal (Geneva, CH), Brandhorst; Heide (Linden, DE)
Assignee: Nordmark Arzneimittel GmbH & Co. KG (Uetersen, DE)
Application Number:13/862,773
Patent Claims:see list of patent claims

Details for Patent 8,765,471

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Smith And Nephew SANTYL collagenase OINTMENT;TOPICAL 101995 001 1965-06-04   Start Trial Nordmark Arzneimittel GmbH & Co. KG (Uetersen, DE) 2023-07-09 RX search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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