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Last Updated: January 18, 2021

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Patent: 8,758,998

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Summary for Patent: 8,758,998
Title:Construction of bifunctional short hairpin RNA
Abstract: A method for designing a bi-shRNA expression cassette encoding a bi-shRNA comprising: selecting one or more target site sequences; providing a backbone sequence comprising a first and a second stem-loop structure, inserting a first passenger strand and a second passenger strand and providing for synthesis of the bi-shRNA expression cassette.
Inventor(s): Rao; Donald (Dallas, TX)
Assignee: Gradalis, Inc. (Carrollton, TX)
Application Number:13/364,053
Patent Claims:see list of patent claims

Details for Patent 8,758,998

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Schering INTRON A interferon alfa-2b VIAL 103132 003 1986-06-04   Start Trial Gradalis, Inc. (Carrollton, TX) 2026-11-09 RX search
Schering INTRON A interferon alfa-2b VIAL 103132 002 1986-06-04   Start Trial Gradalis, Inc. (Carrollton, TX) 2026-11-09 RX search
Schering INTRON A interferon alfa-2b VIAL 103132 001 1986-06-04   Start Trial Gradalis, Inc. (Carrollton, TX) 2026-11-09 RX search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

International Patent Family for US Patent 8,758,998

Country Patent Number Estimated Expiration
United States of America 2007248659   Start Trial
United States of America 2008269474   Start Trial
United States of America 2010166845   Start Trial
United States of America 2012183955   Start Trial
United States of America 2012251617   Start Trial
United States of America 2013071928   Start Trial
United States of America 2013078719   Start Trial
>Country >Patent Number >Estimated Expiration

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Baxter
McKinsey
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Medtronic

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