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Last Updated: November 29, 2021

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Patent: 8,734,525

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Summary for Patent: 8,734,525
Title:Osteoinductive demineralized cancellous bone
Abstract: An osteoinductive demineralized bone matrix, corresponding osteoimplants, and methods for making the osteoinductive demineralized bone matrix are disclosed. The osteoinductive demineralized bone matrix may be prepared by providing demineralized bone and altering the collagenous structure of the bone. The osteoinductive demineralized bone matrix may also be prepared by providing demineralized bone and compacting the bone, for example via mechanical compaction, grinding into a particulate, or treatment with a chemical. Additives such as growth factors or bioactive agents may be added to the osteoinductive demineralized bone matrix. The osteoinductive demineralized bone matrix may form an osteogenic osteoimplant. The osteoimplant, when implanted in a mammalian body, may induce at the locus of the implant the full developmental cascade of endochondral bone formation including vascularization, mineralization, and bone marrow differentiation. The osteoinductive demineralized bone matrix may also be used as a delivery device to administer bioactive agents.
Inventor(s): Behnam; Keyvan (Red Bank, NJ), Forsyth; Nanette (Bayville, NJ), Russell; James (Little Silver, NJ), Winterbottom; John (Howell, NJ), Boyce; Todd (Matawan, NJ)
Assignee: Warsaw Orthopedic, Inc. (Warsaw, IN)
Application Number:12/140,025
Patent Claims:see list of patent claims

Details for Patent 8,734,525

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Smith & Nephew, Inc. SANTYL collagenase Ointment 101995 1965-06-04 ⤷  Try it Free 2027-06-15
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

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