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Generated: August 21, 2019

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Patent: 8,734,525

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Summary for Patent: 8,734,525
Title:Osteoinductive demineralized cancellous bone
Abstract: An osteoinductive demineralized bone matrix, corresponding osteoimplants, and methods for making the osteoinductive demineralized bone matrix are disclosed. The osteoinductive demineralized bone matrix may be prepared by providing demineralized bone and altering the collagenous structure of the bone. The osteoinductive demineralized bone matrix may also be prepared by providing demineralized bone and compacting the bone, for example via mechanical compaction, grinding into a particulate, or treatment with a chemical. Additives such as growth factors or bioactive agents may be added to the osteoinductive demineralized bone matrix. The osteoinductive demineralized bone matrix may form an osteogenic osteoimplant. The osteoimplant, when implanted in a mammalian body, may induce at the locus of the implant the full developmental cascade of endochondral bone formation including vascularization, mineralization, and bone marrow differentiation. The osteoinductive demineralized bone matrix may also be used as a delivery device to administer bioactive agents.
Inventor(s): Behnam; Keyvan (Red Bank, NJ), Forsyth; Nanette (Bayville, NJ), Russell; James (Little Silver, NJ), Winterbottom; John (Howell, NJ), Boyce; Todd (Matawan, NJ)
Assignee: Warsaw Orthopedic, Inc. (Warsaw, IN)
Application Number:12/140,025
Patent Claims:see list of patent claims

Details for Patent 8,734,525

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Advance Biofactures SANTYL collagenase VIAL 101995 001 1965-06-04   Try a Free Trial Warsaw Orthopedic, Inc. (Warsaw, IN) 2027-06-15 RX search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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