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Last Updated: September 28, 2020

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Patent: 8,709,443

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Summary for Patent: 8,709,443
Title:Reovirus for the treatment of cellular proliferative disorders
Abstract: Methods for treating proliferative disorders, by administering reovirus to a Ras-mediated proliferative disorder, are disclosed. The reovirus is administered so that it ultimately directly contacts ras-mediated proliferating cells. Proliferative disorders include but are not limited to neoplasms. Human reovirus, non-human mammalian reovirus, and/or avian reovirus can be used. If the reovirus is human reovirus, serotype 1 (e.g., strain Lang), serotype 2 (e.g., strain Jones), serotype 3 (e.g., strain Dearing or strain Abney), as well as other serotypes or strains of reovirus can be used. Combinations of more than one type and/or strain of reovirus can be used, as can reovirus from different species of animal. Either solid neoplasms or hematopoietic neoplasms can be treated.
Inventor(s): Lee; Patrick W. K. (Halifax, CA), Strong; James (Calgary, CA), Coffey; Matthew C. (Calgary, CA)
Assignee: Oncolytics Biotech Inc. (Calgary, Alberta, CA)
Application Number:13/287,399
Patent Claims:see list of patent claims

Details for Patent 8,709,443

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Genentech HERCEPTIN trastuzumab VIAL; INTRAVENOUS 103792 001 1998-09-25   Start Trial Oncolytics Biotech Inc. (Calgary, Alberta, CA) 2019-02-24 RX Orphan search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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