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Last Updated: October 1, 2020

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Patent: 8,680,256

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Summary for Patent: 8,680,256
Title:Methods for producing inducible and/or repressible expression active linear RNA interference cassettes and inducible and/or repressible expression active linear gene cassettes and their uses
Abstract: The present invention relates to a (first) method for producing inducible and/or repressible expression active linear RNA interference constructs comprising a PCR amplification of a source polynucleotide comprising the inhibitory RNA coding sequence of interest or comprising a PCR amplification of a DNA source comprising a promoter using a reverse primer comprising the inhibitory RNA coding sequence of interest. The present invention furthermore relates to a (second) method for producing inducible and/or repressible expression active linear gene constructs comprising a PCR amplification of a source expression polynucleotide comprising a promoter sequence and the DNA sequence of interest or comprising a PCR amplification using the DNA sequence as a template. The present invention furthermore relates to libraries, arrays, cells and cell lines and kits utilizing the inducible and/or repressible expression active linear RNA interference constructs or the inducible and/or repressible expression active linear gene constructs.
Inventor(s): Abu Khabar; Khalid S. (Riyadh, SA)
Assignee: King Faisal Specialist Hospital & Research Centre (Riyadh, SA)
Application Number:13/001,303
Patent Claims:see list of patent claims

Details for Patent 8,680,256

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Schering INTRON A interferon alfa-2b VIAL 103132 003 1986-06-04   Start Trial King Faisal Specialist Hospital & Research Centre (Riyadh, SA) 2028-06-27 RX search
Schering INTRON A interferon alfa-2b VIAL 103132 002 1986-06-04   Start Trial King Faisal Specialist Hospital & Research Centre (Riyadh, SA) 2028-06-27 RX search
Schering INTRON A interferon alfa-2b VIAL 103132 001 1986-06-04   Start Trial King Faisal Specialist Hospital & Research Centre (Riyadh, SA) 2028-06-27 RX search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

International Patent Family for US Patent 8,680,256

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