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Last Updated: September 27, 2020

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Patent: 8,680,241

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Summary for Patent: 8,680,241
Title:Humanized antibodies specific for HSP65-derived peptide-6 methods and uses thereof
Abstract: The present invention relates to humanized antibodies that specifically bind a polypeptide comprising peptide-6 as denoted by SEQ ID NO. 15, that is an HSP65 derived peptide. More specifically, the invention relates to humanized anti-peptide-6 antibodies, compositions, methods and uses thereof for the treatment of immune-related disorders, specifically, inflammatory disorders such as arthritis, IBD, psoriasis, diabetes and MS. The invention further provides combined compositions and kit combining the humanized antibodies of the invention and at least one anti-inflammatory agent, as well as uses of the humanized antibodies in diagnostic kits and methods.
Inventor(s): Naparstek; Yaakov (Jerusalem, IL), Yair; Shira (Jerusalem, IL)
Assignee: Protab Ltd. (Jerusalem, IL)
Application Number:13/392,548
Patent Claims:see list of patent claims

Details for Patent 8,680,241

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Genentech RITUXAN rituximab SOLUTION;INTRAVENOUS 103705 001 1997-11-26   Start Trial Protab Ltd. (Jerusalem, IL) 2029-09-06 RX search
Genentech RITUXAN rituximab SOLUTION;INTRAVENOUS 103705 002 1997-11-26   Start Trial Protab Ltd. (Jerusalem, IL) 2029-09-06 RX search
Centocor Inc REMICADE infliximab VIAL 103772 001 1998-08-24   Start Trial Protab Ltd. (Jerusalem, IL) 2029-09-06 RX Orphan search
Immunex ENBREL etanercept VIAL; SUBCUTANEOUS 103795 001 1998-11-02   Start Trial Protab Ltd. (Jerusalem, IL) 2029-09-06 RX Orphan search
Immunex ENBREL etanercept SYRINGE 103795 002 1998-11-02   Start Trial Protab Ltd. (Jerusalem, IL) 2029-09-06 RX Orphan search
Biovitrum Ab KINERET anakinra VIAL; SUBCUTANEOUS 103950 001 2001-11-14   Start Trial Protab Ltd. (Jerusalem, IL) 2029-09-06 RX search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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