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Last Updated: September 28, 2020

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Patent: 8,663,639

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Summary for Patent: 8,663,639
Title:Formulations for treating ocular diseases and conditions
Abstract: Diseases and conditions associated with tissues of the body, including but not limited to tissues in the eye, can be effectively treated, prevented, inhibited, onset delayed, or regression caused by administering therapeutic agents to those tissues. Described herein are liquid formulations which deliver a variety of therapeutic agents, including but not limited to rapamycin, to a subject for an extended period of time; liquid formulations which form a non-dispersed mass when placed in an aqueous medium of a subject; non-dispersed mass-forming liquid formulations which form a gel or gel-like substance in an aqueous medium; liquid formulations, comprising a therapeutic agent and a plurality of polymers; and methods for delivering therapeutic agents to a subject for an extended period of time using the liquid formulations. The liquid formulation may be placed in an aqueous medium of a subject, including but not limited to via intraocular or periocular administration, or placement proximate to a site of a disease or condition to be treated in a subject. A method may be used to administer rapamycin to treat or prevent angiogenesis, choroidal neovascularization, or age-related macular degeneration, or wet age-related macular degeneration in a subject. The liquid formulations may comprise rapamycin or other therapeutic agents.
Inventor(s): Dor; Philippe J. M. (Cupertino, CA), Mudumba; Sreenivasu (Union City, CA), Nivaggioli; Thierry (Atherton, CA), Weber; David A. (Danville, CA), Farooq; Sidiq (Newark, CA), Takhar; Sudeep (Fremont, CA)
Assignee: Santen Pharmaceutical Co., Ltd. (Osaka, JP)
Application Number:12/193,686
Patent Claims:see list of patent claims

Details for Patent 8,663,639

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Genentech LUCENTIS ranibizumab INJECTABLE; INJECTION 125156 001 2006-06-30   Start Trial Santen Pharmaceutical Co., Ltd. (Osaka, JP) 2025-02-09 RX search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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