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Last Updated: September 27, 2020

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Patent: 8,663,599

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Summary for Patent: 8,663,599
Title:Pharmaceutical composition of nanoparticles
Abstract: The invention discloses a pharmaceutical composition of pH-sensitive liposome nanoparticles for lodging in a target tissue cell in situ of an animal subject, the nanoparticles comprising a proton-releasing photosensitive compound that releases protons upon photolysis, wherein the compound is in vesicles of the liposomes. A light or UV light is provided to induce the photosensitive compound to release the protons, thus the released protons causing the pH-sensitive liposome to decompose.
Inventor(s): Sung; Hsing-Wen (Hsinchu, TW), Liao; Zi-Xian (Hsinchu, TW), Chung; Min-Fan (Hsinchu, TW), Chen; Ko-Jie (Hsinchu, TW), Cheng; Po-Yuan (Hsinchu, TW), Tu; Hosheng (Newport Beach, CA)
Assignee: GP Medical, Inc. (Newport Beach, CA) National Tsing Hua University (Hsinchu, TW)
Application Number:13/682,929
Patent Claims:see list of patent claims

Details for Patent 8,663,599

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Genentech RITUXAN rituximab SOLUTION;INTRAVENOUS 103705 001 1997-11-26   Start Trial GP Medical, Inc. (Newport Beach, CA) National Tsing Hua University (Hsinchu, TW) 2024-10-05 RX search
Genentech RITUXAN rituximab SOLUTION;INTRAVENOUS 103705 002 1997-11-26   Start Trial GP Medical, Inc. (Newport Beach, CA) National Tsing Hua University (Hsinchu, TW) 2024-10-05 RX search
Genentech Inc RITUXAN HYCELA rituximab; hyaluronidase (human recombinant) SOLUTION;SUBCUTANEOUS 761064 001 2017-06-22   Start Trial GP Medical, Inc. (Newport Beach, CA) National Tsing Hua University (Hsinchu, TW) 2024-10-05 RX Orphan search
Genentech Inc RITUXAN HYCELA rituximab; hyaluronidase (human recombinant) SOLUTION;SUBCUTANEOUS 761064 002 2017-06-22   Start Trial GP Medical, Inc. (Newport Beach, CA) National Tsing Hua University (Hsinchu, TW) 2024-10-05 RX Orphan search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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