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Last Updated: February 18, 2020

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Patent: 8,642,582

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Summary for Patent: 8,642,582
Title:Morpholinone compounds as factor IXa inhibitors
Abstract: The present invention provides a compound of Formula (I) ##STR00001## as described herein, or a pharmaceutically acceptable salt or a solvate thereof. The present invention also provides pharmaceutical compositions comprising one or more said compounds, and methods for using said compounds for treating or preventing a thromboses, embolisms, hypercoagulability or fibrotic changes.
Inventor(s): Nishida; Hidemitsu (Tokyo, JP), Saitoh; Fumihiko (Tokyo, JP), Hirabayashi; Tomokazu (Tokyo, JP), Chackalamannil; Samuel (Califon, NJ), Chan; Tin-Yau (Edison, NJ), Chelliah; Mariappan V. (Edison, NJ), Clasby; Martin C. (Plainsboro, NJ), Dwyer; Michael (Scotch Plains, NJ), Greenlee; William J. (Teaneck, NJ), Xia; Yan (Edison, NJ)
Assignee: Merck Sharp & Dohme Corp. (Rahway, NJ)
Application Number:12/744,736
Patent Claims:see list of patent claims

Details for Patent 8,642,582

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Genentech TNKASE tenecteplase VIAL 103909 001 2000-06-02   Start Trial Merck Sharp & Dohme Corp. (Rahway, NJ) 2039-02-26 RX search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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