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Last Updated: December 1, 2021

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Patent: 8,642,327

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Summary for Patent: 8,642,327
Title:Vector for inhibition-based high-throughput screen strategy
Abstract: A method for screening cells with high level expression of a target protein is disclosed. The method includes introducing into a plurality of host cells a DNA construct that encodes both a target protein and an inhibitor to an endogenous selectable marker in the host cells, screening host cells harboring the DNA construct for the expression of the endogenous selectable marker, and isolating cells with reduced expression of the selectable marker. Also disclosed is a DNA construct configured to express both the target protein and the inhibitor inside the host cell.
Inventor(s): Liu; Wei-Kuang (Taipei, TW), Ding; Min-Pey (Taipei County, TW)
Assignee: Scinopharm Taiwan, Ltd. (Tainan County, TW)
Application Number:13/231,436
Patent Claims:see list of patent claims

Details for Patent 8,642,327

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Genentech, Inc. HERCEPTIN trastuzumab For Injection 103792 1998-09-25 ⤷  Try it Free 2029-06-11
Genentech, Inc. HERCEPTIN trastuzumab For Injection 103792 2017-02-10 ⤷  Try it Free 2029-06-11
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

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