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Last Updated: December 3, 2021

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Patent: 8,637,306

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Summary for Patent: 8,637,306
Title:Production of carrier-peptide conjugates using chemically reactive unnatural amino acids
Abstract: Provided are methods of making carrier polypeptide that include incorporating a first unnatural amino acid into a carrier polypeptide variant, incorporating a second unnatural amino acid into a target polypeptide variant, and reacting the first and second unnatural amino acids to produce the conjugate. Conjugates produced using the provided methods are also provided. In addition, orthogonal translation systems in methylotrophic yeast and methods of using these systems to produce carrier and target polypeptide variants comprising unnatural amino acids are provided.
Inventor(s): Young; Travis (San Diego, CA), Schultz; Peter G. (La Jolla, CA)
Assignee: The Scripps Research Institute (La Jolla, CA)
Application Number:12/653,274
Patent Claims:see list of patent claims

Details for Patent 8,637,306

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Eli Lilly And Company HUMULIN R U-100 insulin human Injection 018780 1982-10-28 ⤷  Try it Free 2028-12-10
Eli Lilly And Company HUMULIN R U-500 insulin human Injection 018780 2015-12-29 ⤷  Try it Free 2028-12-10
Eli Lilly And Company HUMULIN R U-100 insulin human Injection 018780 1998-08-06 ⤷  Try it Free 2028-12-10
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

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