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Generated: September 22, 2019

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Patent: 8,637,306

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Summary for Patent: 8,637,306
Title:Production of carrier-peptide conjugates using chemically reactive unnatural amino acids
Abstract: Provided are methods of making carrier polypeptide that include incorporating a first unnatural amino acid into a carrier polypeptide variant, incorporating a second unnatural amino acid into a target polypeptide variant, and reacting the first and second unnatural amino acids to produce the conjugate. Conjugates produced using the provided methods are also provided. In addition, orthogonal translation systems in methylotrophic yeast and methods of using these systems to produce carrier and target polypeptide variants comprising unnatural amino acids are provided.
Inventor(s): Young; Travis (San Diego, CA), Schultz; Peter G. (La Jolla, CA)
Assignee: The Scripps Research Institute (La Jolla, CA)
Application Number:12/653,274
Patent Claims:see list of patent claims

Details for Patent 8,637,306

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Nps Pharms Inc NATPARA parathyroid hormone INJECTABLE;INJECTION 125511 001 2015-01-23   Try a Free Trial The Scripps Research Institute (La Jolla, CA) 2028-12-10 RX Orphan search
Nps Pharms Inc NATPARA parathyroid hormone INJECTABLE;INJECTION 125511 002 2015-01-23   Try a Free Trial The Scripps Research Institute (La Jolla, CA) 2028-12-10 RX Orphan search
Nps Pharms Inc NATPARA parathyroid hormone INJECTABLE;INJECTION 125511 003 2015-01-23   Try a Free Trial The Scripps Research Institute (La Jolla, CA) 2028-12-10 RX Orphan search
Nps Pharms Inc NATPARA parathyroid hormone INJECTABLE;INJECTION 125511 004 2015-01-23   Try a Free Trial The Scripps Research Institute (La Jolla, CA) 2028-12-10 RX Orphan search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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