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Last Updated: October 1, 2020

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Patent: 8,636,997

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Summary for Patent: 8,636,997
Title:Method of treating multiple sclerosis with interferon-beta and an IL-2R antagonist
Abstract: Disclosed is a method of administering an interleukin-2 receptor (IL-2R) antagonist to a subject to treat an autoimmune disease. In particular embodiments, the IL-2R antagonist is an anti-IL-2R monoclonal antibody specific for one or more chains of the IL-2R, such as the alpha-chain, for example daclizumab. In other particular embodiments the autoimmune disease is multiple sclerosis. In certain embodiments administration of interferon-beta is combined with administration of an antagonist of the IL-2R to provide significant clinical improvement in a subject with an autoimmune disease.
Inventor(s): Martin; Roland (Bethesda, MD), McFarland; Henry (Gaithersburg, MD), Bielekova; Bibiana (Kensington, MD), Waldmann; Thomas (Silver Spring, MD)
Assignee: The United States of America as represented by the Secretary of the Department of Health and Human Services (Washington, DC) N/A (N/A)
Application Number:13/612,763
Patent Claims:see list of patent claims

Details for Patent 8,636,997

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Biogen ZINBRYTA daclizumab INJECTABLE;INJECTION 761029 001 2017-05-26   Start Trial The United States of America as represented by the Secretary of the Department of Health and Human Services (Washington, DC) N/A (N/A) 2022-06-28 RX search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

International Patent Family for US Patent 8,636,997

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Serving leading biopharmaceutical companies globally:

Express Scripts
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