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Last Updated: November 29, 2021

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Patent: 8,618,289

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Summary for Patent: 8,618,289
Title:RAF kinase modulator compounds and methods of use thereof
Abstract: Compounds according to formula (I), compositions and methods are provided for modulating the activity of RAF kinases, including BRAF kinase and for the treatment, prevention, or amelioration of one or more symptoms of disease or disorder mediated by RAF kinases. Formula (I): or a pharmaceutically acceptable salt, solvate, clathrate of hydrate thereof, wherein X is O or S(O).sub.t; R.sup.a is O or S. ##STR00001##
Inventor(s): Abraham; Sunny (San Diego, CA), Bhagwat; Shripad S. (San Diego, CA), Campbell; Brian T. (Burlington, NJ), Chao; Qi (San Diego, CA), Faraoni; Raffaella (San Diego, CA), Holladay; Mark W. (San Diego, CA), Lai; Andiliy G. (San Diego, CA), Rowbottom; Martin W. (San Diego, CA), Setti; Eduardo (San Mateo, CA), Sprankle; Kelly G. (Vista, CA)
Assignee: Ambit Biosciences Corporation (San Diego, CA)
Application Number:12/933,402
Patent Claims:see list of patent claims

Details for Patent 8,618,289

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Genentech, Inc. AVASTIN bevacizumab Injection 125085 2004-02-26 ⤷  Try it Free 2028-03-17
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

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