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Last Updated: September 27, 2020

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Patent: 8,617,554

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Summary for Patent: 8,617,554
Title:Anti-human CD52 immunoglobulins
Abstract: The present invention relates to humanized immunoglobulins, mouse monoclonal antibodies and chimeric antibodies that have binding specificity for human CD52. The present invention further relates to a humanized immunoglobulin light chain and a humanized immunoglobulin heavy chain. The invention also relates to isolated nucleic acids, recombinant vectors and host cells that comprise a sequence which encodes a humanized immunoglobulin or immunoglobulin light chain or heavy chain, and to a method of preparing a humanized immunoglobulin. The humanized immunoglobulins can be used in therapeutic applications to treat, for example, autoimmune disease, cancer, non-Hodgkin\'s lymphoma, multiple sclerosis and chronic lymphocytic leukemia.
Inventor(s): Roberts; Bruce L (Southborough, MA), Shankara; Srinivas (Shrewsbury, MA), Brondyk; William Harold (Mansfield, MA), Siders; William M (Franklin, MA)
Assignee: Genzyme Corporation (Cambridge, MA)
Application Number:13/320,019
Patent Claims:see list of patent claims

Details for Patent 8,617,554

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Genzyme CAMPATH alemtuzumab VIAL; INTRAVENOUS 103948 001 2001-05-07   Start Trial Genzyme Corporation (Cambridge, MA) 2029-05-13 RX Orphan search
Genzyme CAMPATH alemtuzumab VIAL; INTRAVENOUS 103948 002 2001-05-07   Start Trial Genzyme Corporation (Cambridge, MA) 2029-05-13 RX Orphan search
Genzyme LEMTRADA alemtuzumab INJECTABLE;INJECTION 103948 003 2001-05-07   Start Trial Genzyme Corporation (Cambridge, MA) 2029-05-13 RX Orphan search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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