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Generated: July 23, 2019

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Patent: 8,609,328

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Summary for Patent: 8,609,328
Title:Method of separating pancreatic islet
Abstract: The present invention provides a pancreatic islet isolation method comprising the steps of (1) injecting a protection solution containing a protease inhibitor into the pancreatic duct of an procured pancreas; (3) digesting the pancreas into which the protection solution has been injected; and (4) purifying the digested pancreatic tissue using a purification solution containing a density gradient reagent. The present invention also provides a protection solution for injection into the pancreatic duct, a pancreas preservation solution for the two-layer method, and an islet purification solution.
Inventor(s): Matsumoto; Shinichi (Kyoto, JP), Wada; Hiromi (Kyoto, JP), Noguchi; Hirofumi (Kyoto, JP)
Assignee: Otsuka Pharmaceutical Factory, Inc. (Naruto-shi, Tokushima, JP)
Application Number:13/624,309
Patent Claims:see list of patent claims

Details for Patent 8,609,328

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Patent Expiration Status Orphan Source
Advance Biofactures SANTYL collagenase VIAL 101995 001 1965-06-04 ➤ Sign Up Otsuka Pharmaceutical Factory, Inc. (Naruto-shi, Tokushima, JP) ➤ Sign Up RX search
Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Patent Expiration Status Orphan Source

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International Patent Family for US Patent 8,609,328

Country Patent Number Publication Date
World Intellectual Property Organization (WIPO) 2006068226 Jun 29, 2006
United States of America 2008038823 Feb 14, 2008
United States of America 2013017606 Jan 17, 2013
United States of America 8288085 Oct 16, 2012
South Korea 101160198 Jul 09, 2012
South Korea 20070095956 Oct 01, 2007
Japan 4324679 Sep 02, 2009
Country Patent Number Publication Date

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Serving hundreds of leading biopharmaceutical companies globally:

Citi
Queensland Health
Express Scripts
Covington
Merck
Cipla

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