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Last Updated: October 1, 2020

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Patent: 8,604,176

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Summary for Patent: 8,604,176
Title:Protein-responsive RNA control devices and uses thereof
Abstract: The invention described herein relates to an RNA-based control device that senses the presence and/or concentration of at least one protein ligand, preferably through its protein-binding aptamer domain, and regulates a target gene expression through alternative splicing of the target gene in which the RNA-based control device is integrated. The device has uses in therapeutic as well as diagnostic applications.
Inventor(s): Smolke; Christina D. (Menlo Park, CA), Culler; Stephanie J. (Placentia, CA)
Assignee: California Institute of Technology (Pasadena, CA)
Application Number:12/943,350
Patent Claims:see list of patent claims

Details for Patent 8,604,176

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Schering INTRON A interferon alfa-2b VIAL 103132 003 1986-06-04   Start Trial California Institute of Technology (Pasadena, CA) 2029-11-10 RX search
Schering INTRON A interferon alfa-2b VIAL 103132 002 1986-06-04   Start Trial California Institute of Technology (Pasadena, CA) 2029-11-10 RX search
Schering INTRON A interferon alfa-2b VIAL 103132 001 1986-06-04   Start Trial California Institute of Technology (Pasadena, CA) 2029-11-10 RX search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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