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Generated: September 16, 2019

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Patent: 8,603,780

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Summary for Patent: 8,603,780
Title:Methods and compositions for enhanced expression and secretion of proteins
Abstract: Optimized signal peptide coding sequences for enhanced expression and secretion of protein from a cell and related compositions and methods are described. The optimized signal peptide coding sequence encodes an mRNA that contains at least one hairpin structure immediately downstream of the initiation codon. Methods for obtaining the optimized signal peptide coding sequences and methods for enhanced expression and secretion of proteins using the optimized signal peptide coding sequences are also described.
Inventor(s): Wang; Zhuying (Monmouth Junction, NJ), Liu; Xiaowu (Nanjing, CN)
Assignee: Nanjingjinsirui Science & Technology Biology Corp. (Nanjing, CN)
Application Number:13/550,120
Patent Claims:see list of patent claims

Details for Patent 8,603,780

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Genentech RITUXAN rituximab VIAL 103705 001 1997-11-26   Try a Free Trial Nanjingjinsirui Science & Technology Biology Corp. (Nanjing, CN) 2031-07-15 RX search
Genentech HERCEPTIN trastuzumab VIAL; INTRAVENOUS 103792 001 1998-09-25   Try a Free Trial Nanjingjinsirui Science & Technology Biology Corp. (Nanjing, CN) 2031-07-15 RX Orphan search
Amgen ARANESP darbepoetin alfa VIAL; INTRAVENOUS 103951 001 2001-09-17   Try a Free Trial Nanjingjinsirui Science & Technology Biology Corp. (Nanjing, CN) 2031-07-15 RX search
Amgen ARANESP darbepoetin alfa VIAL; INTRAVENOUS 103951 002 2001-09-17   Try a Free Trial Nanjingjinsirui Science & Technology Biology Corp. (Nanjing, CN) 2031-07-15 RX search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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