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Last Updated: September 28, 2020

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Patent: 8,603,014

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Summary for Patent: 8,603,014
Title:Hands-free operator-independent transcranial ultrasound apparatus and methods
Abstract: Disclosed is a \"hands-free\", autonomously operating, battery-powered apparatus with electronic programmable actuation circuitry for non-invasive ultrasonic treatment of ischemic stroke, microatheromas of the cerebral vasculature, intracranial hypertension, and other cerebrovascular pathologies such as hypoperfusion associated with migraine. The apparatus is provided with registration members to facilitate stereotactic placement of the headset on the skull with respect to target intracranial anatomy. Once fitted in place on the skull and activated, the device does not require clinical intervention during operation; does not need skilled technical adjustment of the waveform patterns; and achieves therapeutic results with power consumption of less than 400 mAmp-hr, thus permitting extended portable operation without external power and eliminating the need for assisted cooling. Using a device of the invention, transcranial ultrasound may be self-administered. The device has application in therapeutic methods, such as methods for treating stroke or migraine, for non-invasively augmenting drug action, and for release or dispersal of endogenous neurovascular mediators.
Inventor(s): Alleman; Anthony John (Sherwood, OR), Barnard; William (Maple Valley, WA), Radford; Randal Lee (Burien, WA)
Assignee: Cerevast Therapeutics, Inc. (Redmond, WA)
Application Number:13/209,408
Patent Claims:see list of patent claims

Details for Patent 8,603,014

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Microbix Biosystems KINLYTIC urokinase INJECTABLE;INJECTION 021846 001 1978-01-16   Start Trial Cerevast Therapeutics, Inc. (Redmond, WA) 2039-02-26 DISCN search
Microbix Biosystems KINLYTIC urokinase INJECTABLE;INJECTION 021846 002 1978-01-16   Start Trial Cerevast Therapeutics, Inc. (Redmond, WA) 2039-02-26 DISCN search
Microbix Biosystems KINLYTIC urokinase INJECTABLE;INJECTION 021846 003 1978-01-16   Start Trial Cerevast Therapeutics, Inc. (Redmond, WA) 2039-02-26 DISCN search
Genentech ACTIVASE alteplase VIAL; SINGLE-USE 103172 001 1987-11-13   Start Trial Cerevast Therapeutics, Inc. (Redmond, WA) 2039-02-26 RX search
Genentech ACTIVASE alteplase VIAL; SINGLE-USE 103172 002 1987-11-13   Start Trial Cerevast Therapeutics, Inc. (Redmond, WA) 2039-02-26 RX search
Genentech CATHFLO ACTIVASE alteplase VIAL 103172 003 1987-11-13   Start Trial Cerevast Therapeutics, Inc. (Redmond, WA) 2039-02-26 RX search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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