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Last Updated: September 26, 2020

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Patent: 8,597,613

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Summary for Patent: 8,597,613
Title:Radiolabeled lymphatic staining agents and methods for making
Abstract: A radiolabeled lymphatic staining agent is mixed on site with a much larger amount, on a weight basis, of a non-radiolabeled lymphatic staining agent to form an injectable radiolabeled lymphatic staining agent suitable for surgical use in humans. Preferably, the radiolabel is I-125, because it has a 60-day half-life which enables it to be made off-site. The preferred radiolabeled lymphatic staining agent is iodinated methylene blue, because it can be mixed with a range of non-radioactive lymphatic staining agents, for example isosulfan blue, methylene blue, patent blue, and patent blue V, to provide the injected agent with sufficient radioactivity to enable machine detection. A method for making radioiodinated methylene blue is also disclosed.
Inventor(s): Maloney; Thomas J. (Friendswood, TX), Camp, Jr.; Arthur E. (Richmond, TX), Hernandez; Jesse J. (Alvin, TX)
Assignee: Iso-Tex Diagnostics, Inc (Friendswood, TX)
Application Number:10/884,561
Patent Claims:see list of patent claims

Details for Patent 8,597,613

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Merck Sharp & Dohme Corp. ZOSTAVAX zoster vaccine live INJECTION, POWDER, LYOPHILIZED, FOR SUSPENSION 125123 001 2006-05-25   Start Trial Iso-Tex Diagnostics, Inc (Friendswood, TX) 2039-09-22 search
Merck Sharp & Dohme Corp. ZOSTAVAX zoster vaccine live INJECTION, POWDER, LYOPHILIZED, FOR SUSPENSION 125123 1 2006-05-25   Start Trial Iso-Tex Diagnostics, Inc (Friendswood, TX) 2039-09-22 search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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