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Last Updated: December 2, 2021

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Patent: 8,591,943

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Summary for Patent: 8,591,943
Title:Pyrazolo[1,5-a]pyrimidine derivatives as mTOR inhibitors
Abstract: The present invention provides methods for inhibiting mTOR using pyrazolo[1,5-a]pyrimidine compounds and methods of treatment, prevention, inhibition, or amelioration of one or more diseases associated with mTOR using such compounds.
Inventor(s): Deng; Yongqi (Newton, MA), Sun; Binyuan (Chestnut Hill, MA), Zeng; Hongbo (Westford, MA), Richards; Matthew (Somerville, MA), Shipps, Jr.; Gerald W. (Stoneham, MA), Cheng; Cliff C. (Cambridge, MA), Zhao; Yinyan (Rockville, MD), McRiner; Andrew (Melrose, MA), Meng; Zhaoyang (Lansdale, PA), Nan; Yang (Lansdale, PA), Patel; Mehul F. (Willow Grove, PA), Wrona; Iwona E. (Sharon, MA), Reddy; Panduranga Adulla (Walpole, MA), Eklov; Brian M. (Kalamazoo, MI), Tang; Shuyi (Belmont, MA), Liu; Duan (Arlington, MA), Mandal; Amit K. (Shrewsbury, MA), Zhao; Lianyun (Blue Bell, PA), Siddiqui; M. Arshad (Newton, MA)
Assignee: Merck Sharp & Dohme Corp. (Rahway, NJ)
Application Number:13/263,193
Patent Claims:see list of patent claims

Details for Patent 8,591,943

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Recordati Rare Diseases, Inc. ELSPAR asparaginase For Injection 101063 1978-01-10 ⤷  Free Forever Trial 2039-02-26
Merck Sharp & Dohme Corp. INTRON A interferon alfa-2b For Injection 103132 1986-06-04 ⤷  Free Forever Trial 2039-02-26
Merck Sharp & Dohme Corp. INTRON A interferon alfa-2b For Injection 103132 ⤷  Free Forever Trial 2039-02-26
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

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