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Last Updated: December 6, 2021

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Patent: 8,569,471

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Summary for Patent: 8,569,471
Title:Stem cell beacon
Abstract: The invention relates to methods and compositions for selectively directing stem cells to a target tissue within a subject using a system that employs one or more vectors that contain a gene switch/biosensor, a tissue-specific promoter, a gene encoding a stem cell-attracting chemokine, and a gene amplification system. In one embodiment, a stem cell-attracting chemokine is expressed in damaged tissue using a stimulus-responsive vector system. The stimulus can be a physiological stimulus associated with cell injury, such as hypoxia or elevated glucose levels, for example. Expression of the chemokine increases the trafficking of stem cells to the damaged tissue.
Inventor(s): Phillips; M. Ian (Claremont, CA), Tang; Yao Liang (Claremont, CA)
Assignee: University of South Florida (Tampa, FL)
Application Number:13/299,991
Patent Claims:see list of patent claims

Details for Patent 8,569,471

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Nps Pharmaceuticals, Inc. NATPARA parathyroid hormone For Injection 125511 2015-01-23 ⤷  Free Forever Trial 2023-08-11
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

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