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Last Updated: February 19, 2020

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Patent: 8,563,513

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Summary for Patent: 8,563,513
Title:Parathyroid hormone peptides and parathyroid hormone-related protein peptides and methods of use
Abstract: Provided herein are Parathyroid hormone (PTH) peptides and parathyroid hormone-related protein (PTHrP) peptides (e.g., PTH analogs, PTHrP analogs), and related variants, chemical derivatives, fusion polypeptides, multimeric polypeptides, and peptidomimetics, peptoids, the like. Also provided are their use in methods for activating the PTH receptor in a cell (e.g., an osteoblast), methods of treating a subject with bone loss (e.g., by administration of a PTH peptide or PTHrP peptide (e.g., a PTH analog or PTHrP analog)), methods of ameliorating a symptom associated with osteoporosis in a subject, methods of retarding the progression of osteoporosis in a subject, and methods of regenerating bone in a subject.
Inventor(s): Xu; Huaqiang Eric (Grand Rapids, MI), Pioszak; Augen A. (Edmond, OK), Gardella; Thomas J. (Needham, MA)
Assignee: Van Andel Research Institute (Grand Rapids, MI) The General Hospital Corporation (Boston, MA)
Application Number:13/260,699
Patent Claims:see list of patent claims

Details for Patent 8,563,513

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Nps Pharms Inc NATPARA parathyroid hormone INJECTABLE;INJECTION 125511 001 2015-01-23   Start Trial Van Andel Research Institute (Grand Rapids, MI) The General Hospital Corporation (Boston, MA) 2029-03-27 RX Orphan search
Nps Pharms Inc NATPARA parathyroid hormone INJECTABLE;INJECTION 125511 002 2015-01-23   Start Trial Van Andel Research Institute (Grand Rapids, MI) The General Hospital Corporation (Boston, MA) 2029-03-27 RX Orphan search
Nps Pharms Inc NATPARA parathyroid hormone INJECTABLE;INJECTION 125511 003 2015-01-23   Start Trial Van Andel Research Institute (Grand Rapids, MI) The General Hospital Corporation (Boston, MA) 2029-03-27 RX Orphan search
Nps Pharms Inc NATPARA parathyroid hormone INJECTABLE;INJECTION 125511 004 2015-01-23   Start Trial Van Andel Research Institute (Grand Rapids, MI) The General Hospital Corporation (Boston, MA) 2029-03-27 RX Orphan search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

International Patent Family for US Patent 8,563,513

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