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Last Updated: October 26, 2021

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Patent: 8,557,831

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Summary for Patent: 8,557,831
Title:Compositions and methods for treatment and prevention of insulin resistance
Abstract: Disclosed herein are methods of delaying the onset or treating diabetes that comprises administering a uric acid lowering agent. The inventors have made the remarkable discovery that elevated uric acid levels are not a corollary to insulin resistance, but rather a primary mediator of insulin resistance. Specifically exemplified are methods that involve administering to a patient susceptible to development of diabetes a composition comprising a uric acid lowering agent in a regimen that maintains serum uric acid levels below at least 5.2 to 5.5 mg/dl.
Inventor(s): Johnson; Richard J. (Gainesville, FL), Nakagawa; Takahiko (Gainesville, FL)
Assignee: University of Florida Research Foundation, Inc. (Gainesville, FL)
Application Number:11/572,270
Patent Claims:see list of patent claims

Details for Patent 8,557,831

Applicant Tradename Biologic Ingredient Dosage Form BLA Approval Date Patent No. Expiredate
Sanofi-aventis U.s. Llc ELITEK rasburicase For Injection 103946 2002-07-12 ⤷  Free Forever Trial 2024-07-21
Sanofi-aventis U.s. Llc ELITEK rasburicase For Injection 103946 2006-01-06 ⤷  Free Forever Trial 2024-07-21
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Approval Date >Patent No. >Expiredate

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Serving leading biopharmaceutical companies globally:

Mallinckrodt
Boehringer Ingelheim
Dow
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