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Last Updated: September 21, 2020

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Patent: 8,524,498

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Summary for Patent: 8,524,498
Title:Methods and compositions for homologous recombination in human cells
Abstract: The methods and compositions described herein are based, in part, on the discovery of a stem cell state in human cells that resembles the morphology observed in murine-derived stem cells. Induction of such a state in human stem cells permits an increase in the efficiency of homologous recombination. Thus, the methods and compositions described herein relate to cells and methods for increasing the efficiency of homologous recombination in human stem cells.
Inventor(s): Geijsen; Niels (West Newbury, MA), Buecker; Christa (Somerville, MA)
Assignee: The General Hospital Corporation (Boston, MA)
Application Number:12/791,696
Patent Claims:see list of patent claims

Details for Patent 8,524,498

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Smith And Nephew SANTYL collagenase OINTMENT;TOPICAL 101995 001 1965-06-04   Start Trial The General Hospital Corporation (Boston, MA) 2029-05-29 RX search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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