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Last Updated: September 24, 2020

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Patent: 8,524,226

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Summary for Patent: 8,524,226
Title:Methods of prolonging patency of hemodialysis access
Abstract: The invention provides methods for treating an obstructed biological conduit that include administering to the conduit an agent that can degrade extracellular matrix of obstructing tissue. Particular methods include delivery of an enzyme or a mixture of several enzymes to the area or region of obstruction wherein the enzyme(s) have the capability to degrade extracellular matrix components within the obstruction thereby restoring the normal flow of transported fluid through the conduit. The invention also includes prophylactically dilating a section of conduit to minimize the risk of obstruction formation. The invention further includes methods for prolonging patency of hemodialysis access.
Inventor(s): Franano; F. Nicholas (Kansas City, MO)
Assignee: Proteon Therapeutics, Inc. (Waltham, MA)
Application Number:13/022,070
Patent Claims:see list of patent claims

Details for Patent 8,524,226

Applicant Tradename Biologic Ingredient Dosage Form BLA Number Approval Date Patent No. Assignee Estimated Patent Expiration Status Orphan Source
Smith And Nephew SANTYL collagenase OINTMENT;TOPICAL 101995 001 1965-06-04   Start Trial Proteon Therapeutics, Inc. (Waltham, MA) 2019-09-24 RX search
>Applicant >Tradename >Biologic Ingredient >Dosage Form >BLA >Number >Approval Date >Patent No. >Assignee >Estimated Patent Expiration >Status >Orphan >Source

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